Mississippi
Medical since 2022
Last verified: March 2026 · editorial-team
Possession Limit
N/A
Flower (adult use)
Concentrates
N/A
Per transaction
Home Grow
Not permitted
Personal cultivation
Delivery
Not allowed
Licensed delivery
License Types
cultivation
Cannabis cultivation facility license. Mississippi caps cultivation licenses and requires indoor or greenhouse grows. Facilities are subject to regular MSDH inspections.
Est. Fees
$25,000 application + $25,000 annual license fee
Processing Time
90–180 days
manufacturing
Cannabis processing facility license — covers extraction, infusion, and packaging of medical cannabis products. Must comply with MSDH product testing requirements.
Est. Fees
$25,000 application + $25,000 annual
Processing Time
90–180 days
retail
Medical cannabis dispensary license. Each dispensary must have a licensed pharmacist on staff or available for consultation. Limited to medical patients with qualifying conditions only.
Est. Fees
$15,000 application + $25,000 annual
Processing Time
90–180 days
Testing Laboratory
Cannabis testing facility license. Must maintain ISO 17025 accreditation and be independent of any cultivation, processing, or dispensary operation.
Est. Fees
$15,000 application + $15,000 annual
Processing Time
90–180 days
transport
Cannabis transportation license for moving product between licensed facilities within the state.
Est. Fees
$5,000 application + $5,000 annual
Processing Time
60–90 days
Tax Structure
Excise Rate
No state excise tax on medical cannabis
Sales Tax
Applied
Effective Total
7% state sales tax applies, plus local taxes up to ~10% total
Mississippi does not impose a separate cannabis excise tax on medical products. Standard state sales tax of 7% applies. Local municipalities may add their own sales taxes. The program was designed to keep costs manageable for patients, though pricing remains high due to limited supply.
Regulatory Body
Key Statutes
SB 2095 — Mississippi Medical Cannabis Act
Miss. Code Ann. § 41-137-1 et seq.Signed into law February 2, 2022 by Governor Tate Reeves after voters passed Initiative 65 in 2020 and the state Supreme Court struck it down on a technicality. SB 2095 rebuilt the medical program from scratch through the legislature.
Initiative 65 (struck down)
N/A — invalidated by Mississippi Supreme CourtVoters approved medical cannabis 74% to 26% in November 2020. The Mississippi Supreme Court voided it in May 2021, ruling the ballot initiative process was unconstitutional because the state had only 4 congressional districts, not the required 5. The ruling forced the legislature to act directly.
For Operators
A program built from political wreckage
Mississippi's path to medical cannabis was uniquely messy. Voters overwhelmingly approved Initiative 65 in 2020, but the state Supreme Court threw it out on a procedural technicality tied to redistricting. The legislature stepped in with SB 2095 — a more conservative version that satisfied enough lawmakers to pass. The result is a workable but tightly controlled medical-only program.
Supply constraints shape the market
The MSDH controls license counts. Early licensing rounds were competitive, and the limited number of dispensaries means patients in rural areas may drive significant distances. Cultivation is restricted to indoor and greenhouse facilities, pushing startup costs higher than neighboring states with outdoor grow options.
No recreational path in sight
The same Supreme Court ruling that killed Initiative 65 also effectively broke the state's ballot initiative process. Until the legislature fixes that mechanism or acts on its own, recreational cannabis in Mississippi isn't happening. Operators should plan around a medical-only market for the foreseeable future.
For Consumers
Medical patients only
Mississippi's cannabis program is strictly medical. You need a qualifying condition — cancer, epilepsy, PTSD, chronic pain, and about two dozen others — and a certification from a registered physician. Once certified, you register with the MSDH for a patient ID card. Without one, you can't purchase anything.
Possession limits for patients
Registered patients can purchase up to 3 ounces per month, with a maximum of 6 individual units. Your physician can request a waiver for up to 6 ounces per month for severe conditions. Don't carry more than your allotted amount — law enforcement will check.
What about recreational use?
Still illegal. Mississippi decriminalized possession of up to 30 grams (about an ounce) — meaning you'd get a fine rather than jail time for a first offense. But amounts above that can bring misdemeanor or felony charges depending on quantity. Concentrates and edibles outside the medical program are treated more harshly.
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